CHE 4346 - Biochemistry II

Credits: 3 hrs

This course will build upon an understanding of biomolecular structure and provide a practical treatise of recombinant DNA technology, reactions and regulation of intermediary metabolism, and the biochemistry of genetic systems to include regulatory mechanisms and protein synthesis. The overall objectives of this course are to prepare students with an understanding of: 1) Recent advances in recombinant DNA technology and protein expression, 2) Developments in metabolic regulation in mammals, highlighting some key enzymatic reactions with regulatory properties, 4) DNA replication, repair and recombination, transcription and RNA processing and translation, and 5) Regulation of gene expression. Recent literature on trends and perspectives in Biochemistry will also form part of this course, enabling students to conduct literature searches and critically evaluate some reviews in biochemistry topics. (Three lecture hours per week.) Prerequisite(s): CHE 3327, CHE 3346 and CHE 3146. Corequisite(s): CHE 4246.